“It would change the situation.” Working on a new vaccine against the Corona virus

According to researchers from Flinders University, the vaccine they developed against SARS-CoV-2 may not only protect against disease, but also protect against the spread of the virus.

The preparation contains a synthetically synthesized viral spike protein, developed with the help of artificial intelligence. The vaccine also includes Advax – an adjuvant based on a plant sugar – inulin.

The key to epidemic management is the development of an effective SARS-CoV-2 vaccine that will not only prevent infection and clinical disease, but also prevent transmission of the virus. – Nikolai Petrovsky, research team leader and research director at Vaxine Pty Ltd.

With different countries entering the second, third and even the next wave, the world urgently needs more effective vaccines, especially those that provide strong protection against all new variants of the virus and that are likely to prevent the transmission of the virus. – says the specialist.

Data collected in studies in mice and rodents indicate that the preparation is safe and effective, while at the same time giving hope that it may reduce the risk of disease transmission.

The animals did not release virus particles from their noses or transmit them to other individuals.

We have now collected data on nasal virus secretion and started testing on hamsters in the United States to see exactly whether the vaccine limits transmission of the disease to virus-free animals. Protecting against its transmission will change the situation, and this is what we need to prevent further outbreaks – Inform the professor. Petrovsky.

The vaccine must be stable under conditions achievable in standard refrigerators.

Its phase 2 clinical trial has also ended and the results will be published soon.